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Nusacco®(Sialic Acid)

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Nusacco®(Sialic Acid)

    Sialic Acid Power introduction

    Other Name: N-acetylneuraminic acid (The generic term of sialic acid is N-acetylneuraminic acid, which is a naturally occurring amino sugar that was originally isolated from the submandibular gland mucin, hence the name sialic acid. Sialic acid is a nine-carbon monosaccharide derivative containing an amino group and is a general term for all N- or O-derivatives of neuraminic acid or keto-deoxyindansyl acid (KDN).)

    CAS Number: 131-48-6

    Molecular Formula: C11H19NO9

    Molecular Weight: 309.3

    Assay: 98%

    Country of Origin: China

    Shelf Life: 2 Years

    Specification: Sialic acid 20%-99%


Product description:

Sialic Acid Power introduction

The generic term of sialic acid is N-acetylneuraminic acid, which is a naturally occurring amino sugar that was originally isolated from the submandibular gland mucin, hence the name sialic acid. Sialic acid is a nine-carbon monosaccharide derivative containing an amino group and is a general term for all N- or O-derivatives of neuraminic acid or keto-deoxyindansyl acid (KDN). 

N-acetylneuraminic acid, also known as Sialic acid and NANA, is a key component of important amino sugars that mediate cellular communication. N-acetylneuraminic acid is a naturally-occurring building block for compounds such as glycoproteins and gangliosides, and is therefore widely found in cell membranes, in the plasma and in glandular secretions such as saliva. It is usually present in the form of oligosaccharides, glycolipids or glycoproteins, mainly in the form of short-chain residues at the ends of glycoproteins and glycolipids.


The main sources of sialic acid are breast milk and dairy products. Including human milk, milk, goat milk, yogurt, the highest content of breast milk colostrum, can reach 1.5 g / liter or more, the average sialic acid content in skim milk powder is 172 mg / 100 g.  Another important source of sialic acid is egg food. In egg white, the content of sialic acid is 0.2 to 0.3%. In humans the brain has the highest sialic acid concentration, where these acids play an important role in neural transmission and ganglioside structure in synaptogenesis.


Specification:

Sialic Acid Power specification

CommodityN-Acetylneuraminic Acid
ITEMSSTANDARDMOA
AppearanceWhite powder
ImpuritiesNo visible impurities
Smell & TasteCharacteristic
Assay≥98.0%HPLC
pH1.8~2.3GB 5009.237
Loss on Drying≤2.0%GB 5009.3
Optical Rotation-30°~-34°GBT 613-2007
Ignition Residue≤2.0%GB 5009.4
Aflatoxin B1≤0.5μg/kgGB 5009.22
Pb≤0.1mg/kgGB 5009.12
As≤0.5mg/kgGB 5009.11
Hg≤0.01mg/kgGB 5009.17
Total Plate Count≤1,000cfu/gGB 4789.2
Yeasts and Moulds≤50cfu/gGB 4789.15
Coliforms≤10cfu/gGB 4789.2
Staphylococcus AureusNot detectedGB 4789.10
SalmonellaNot detectedGB 4789.4
Storage condition Keep container tightly closed in a dry, away from direct light  and well-ventilated place


Application:

Sialic Acid Power application

food additives: lnfant Milk Formula mainly use Sialic Acid Power, N-Acetylneuraminic Acid can effectively improve the development of infant brain and cognition, enhance controlling ability of immune system and have defensive functions against Bacteria. N-acetyl-D-neuraminic acid(NANA)is intended for use in term infant formulas at a maximum use level of50mg/L. This maximum use level of NANA in term infant formulas is based on providing a similar level of NANA as that which occurs in milk from lactating women.

nutritional supplements

pharmaceutical intermediates: N-Acetylneuraminic Acid has Therapeutic effects on amyotrophy, to make body and muscle fulfill energy. Also, it can assist the elderly to prevent the Alzheimer's via daily intake. N-Acetylneuraminic Acid has protective effects on nerve cells. The protease on the surface of the nerve cell membrane combined with N-acetylneuroammonia cannot be degraded by extracellular protease. Moreover, it has strong resistance against virus invasion.

cosmetic materials: N-Acetylneuraminic Acid has wide values and functions in Cosmetic Formulas, specifically as Anti-aging and Whitening. As for anti-aging, it can significantly improve restraining ability against pigmentation, delay the skin aging and promote skin regeneration. On the other hand, as for whitening, it has great effects on inhibiting tyrosine hydroxylase and Dopa hydroxylase activity, meanwhile it can prevent melanin basically.


Do you know the Role of Sialic Acid?

Sialic acid is a derivative of 9-carbon monosaccharide. The name comes from Greek. This is a negatively charged ion that makes the saliva feel smooth. Not only does it have the effect of "inducing" invading bacteria, but it is also currently recognized as a ganglioside transmitter and a component of the brain. Sialic acid can prevent the invasion of germs. Sialic acid is also a receptor for influenza virus, which is the binding site of the influenza virus in mucus cells.

Function:

Sialic Acid Power advantage

a. Improve brain development and memory enhancement

b. Cell membrane structure composition, enhance cell activity thus improving human immunity

c. Promote the absorption of mineral and vitamins in the intestines

d. Delay brain function decline and promote damaged nerve repair

e. Whitening and antioxidant    




Certificate Availability

ISO9001

HALAL

ISO22000

Packaging Details

Other

The history of sialic acid in China

Human consumption of sialic acid-containing foods has a long history. The main source of sialic acid is breast milk, dairy products and egg foods, so it can be said that from the moment humans appear on the earth, we are eating sialic acid. Since ancient times, China has had the habit of eating bird's nest. Bird's nest has been listed as a precious tonic. Since the Ming and Qing Dynasties, it has been hailed as the sacred product of beauty. As early as in the Tang Dynasty, China has used bird's nest as an edible treasure. It is the same as the bear's paw and shark's fin. Li Shizhen of the Ming Dynasty praised the bird’s nest in the "Compendium of Compendium of Materia Medica". In Southeast Asia and Japan, bird's nest is also a household nutritional supplement. In bird's nest, the main component of its biological activity, "bird's nest acid", is actually the common name of sialic acid, and its content is as high as 10% or more. The main function of bird's nest is reflected by sialic acid. The experiment also proves that the physiological function of bird's nest acid is as follows: it has the effect of antibacterial detoxification in the intestine; it can improve the absorption capacity of the intestine for vitamins and minerals; because it has the protection and stability effect on cells, it has the effect of prolonging life. Sialic acid develops a range of health supplements for babies, pregnant women, students and the elderly.


As a new nutritional and pharmaceutical formula, N-Acetylneuraminic acid gradually accounted for greater market shares in Infant Formulas and Health Care&Medical. Hot sale various high quality Sialic acid from China leading manufacturer. Our products are efficient, cost effective and deliver more benefits. Welcome to choose us!


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