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Other Name:Pyridoxal 5-phosphate monohydrate
CAS Number:41468-25-1
Molecular Formula:C8H10NO6PH2O
Molecular Weight:265.15
Assay:98%
Standard:CP/USP
Country of Origin:China
Shelf Life:3 Years
Product description:
Pyridoxal phosphate (PLP, pyridoxal 5'-phosphate, P5P), the active form of vitamin B6.
It is an enzyme prosthetic group that acts as a coenzyme in transamination, decarboxylation and deamination reactions such as the conversion of dopa into dopamine; of glutamate into GABA; of histidine to histamine. PLP works mechanistically through formation of a Schiff-base.
Specification:
ITEMS | STANDARDS |
Appearance | Slightly yellow or off-white powder |
Identification | The retention time of the major peak of product corresponds to that of the standard |
Solubility | Very slightly soluble in water, soluble in alkali-OH Soln. |
Melting Point | 140℃~145℃ |
Water (by KF) | NMT10% |
Loss on Drying | NMT0.5% |
Heavy Metals | NMT 10ppm |
Cadmium | NMT 0.5ppm |
Arsenic | NMT 1.5ppm |
Lead | NMT 0.5ppm |
Mercury | NMT 0.1ppm |
Ph(in 0.25% water) | 2.6~3.0 |
Particle Size (Mesh) | 100% through 30 mesh |
Free Vitamin B6 | NMT 0.05% |
Bulk Density | / |
Tapped Density | / |
Toluene | NMT 890ppm |
Ethanol | NMT 5000ppm |
Assay | 98.5~101.0% |
Total Plate Count | NMT 1000cfu/g |
Yeast & Mold | NMT 100cfu/g |
Salmonella | Negative |
E. Coli | Negative |
Staphylococcus Aureus | Negative |
Application:
1) Clinically used to treat Parkinson's disease
2) Promote the transaminase in transamination dopamine levels in the body
3) Used in the treatment of acute or chronic eczema dermatitis nettle examine pustular rash itching seborrheic eczema scaly rash drug eruption deficiency oral inflammation glossitis pregnancy reaction, asthma, etc
4) The main body of vitamin B6
Function:
1. mainly for folic acid antagonists (such as methotrexate, pyrimethamine, benzyl cefalexin and trimethoprim) antidote, it's usually used for prevention of methotrexate dose or overdose treatment caused severe toxic effects.
2. folic acid treatment of the following diseases, such as inflammatory diarrhea and protein-energy malnutrition (poor nutrition), pregnancy or infancy megaloblastic anemia caused by poor.
3. as adjuvant therapy for colon cancer, rectal cancer.
4. combined with 5-FU and treatment of digestive tract tumors or other 5-FU-sensitive tumors. High-dose CF used in conjunction with 5-FU (LF), the basic programme is currently the treatment of colon and rectal cancer.
5. for children with leukemia, lymphoma, and osteosarcoma, such as high dose MTX treatment when rescued.
Certificate Availability
IOS9001
HALAL
KOSHER
Packaging Details
PackingPacked in paper-drums and two plastic-bags inside
For minimal quantity1 kg/aluminium foil bag, 5 bags in a carton.
For large quantity25 kg/fiber carton in net weight; 26.5 kg/fiber carton in gross weight (can be customized).
Other
Storage condition: Stored in a well-sealed container in a dry, cool place, keep away from strong light and heat.
Shelf life: 36months under the conditions above and in its original packaging.
Block 25-26, Zhongbang MOHO, No.2008 Lihu avenue, Wuxi City, Jiangsu China 214125
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