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Pyridoxal 5-Phosphate 98%

    Other Name:Pyridoxal 5-phosphate monohydrate 

    CAS Number:41468-25-1

    Molecular Formula:C8H10NO6PH2O

    Molecular Weight:265.15

    Assay:98%

    Standard:CP/USP

    Country of Origin:China

    Shelf Life:3 Years


Product description:

Pyridoxal phosphate (PLP, pyridoxal 5'-phosphate, P5P), the active form of vitamin B6.

It is an enzyme prosthetic group that acts as a coenzyme in transamination, decarboxylation and deamination reactions such as the conversion of dopa into dopamine; of glutamate into GABA; of histidine to histamine. PLP works mechanistically through formation of a Schiff-base.


Specification:

ITEMS

STANDARDS

Appearance

Slightly yellow or off-white powder

Identification

The retention time of the major peak of product corresponds to that of the standard

Solubility

Very slightly soluble in water, soluble in alkali-OH Soln.

Melting Point

140~145

Water (by  KF)

NMT10%

Loss on Drying

NMT0.5%

Heavy Metals

NMT 10ppm

Cadmium

NMT 0.5ppm

Arsenic

NMT 1.5ppm

Lead

NMT 0.5ppm

Mercury

NMT 0.1ppm

Ph(in 0.25% water)

2.6~3.0

Particle Size (Mesh)

100% through 30 mesh

Free Vitamin B6

NMT 0.05%

Bulk Density

/

Tapped Density

/

Toluene

NMT 890ppm

Ethanol

NMT 5000ppm

Assay

98.5~101.0%

Total Plate Count

NMT 1000cfu/g

Yeast & Mold

NMT 100cfu/g

Salmonella

Negative

E. Coli

Negative

Staphylococcus Aureus

Negative


Application:

1) Clinically used to treat Parkinson's disease

2) Promote the transaminase in transamination dopamine levels in the body

3) Used in the treatment of acute or chronic eczema dermatitis nettle examine pustular rash itching seborrheic eczema scaly rash drug eruption deficiency oral inflammation glossitis pregnancy reaction, asthma, etc
4) The main body of vitamin B6


Function:

1. mainly for folic acid antagonists (such as methotrexate, pyrimethamine, benzyl cefalexin and trimethoprim) antidote, it's usually used for prevention of methotrexate dose or overdose treatment caused severe toxic effects.
2. folic acid treatment of the following diseases, such as inflammatory diarrhea and protein-energy malnutrition (poor nutrition), pregnancy or infancy megaloblastic anemia caused by poor.
3. as adjuvant therapy for colon cancer, rectal cancer.
4. combined with 5-FU and treatment of digestive tract tumors or other 5-FU-sensitive tumors. High-dose CF used in conjunction with 5-FU (LF), the basic programme is currently the treatment of colon and rectal cancer.
5. for children with leukemia, lymphoma, and osteosarcoma, such as high dose MTX treatment when rescued. 

 


Certificate Availability

IOS9001

HALAL

KOSHER

Packaging Details

Other

Storage condition: Stored in a well-sealed container in a dry, cool place, keep away from strong light and heat.

Shelf life: 36months under the conditions above and in its original packaging. 


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